Research Interest
Bioinorganic Chemistry
Our group is interested in the synthesis and characterization of novel coordination complexes which could mimic the active site (metal-site) of different metalloenzymes.
Galactose Oxidase
Mn Superoxide Dismutase
Fe Superoxide Dismutase
Protein Aggregation and Interaction of Metal Ions
Our group is interested in the synthesis and characterization of novel transition metal complexes for protein interaction and prevention of Aβ amyloid (1-42 peptide) aggregation in Alzheimer disease.
Organometallic Chemistry and Catalysis
Organometallic chemistry is an important area for the functionalization of the remote C-H bond. We are interested in C-H activation stoichiometrically. This prompted us, particularly in the development of novel catalytic methodologies for multiple C-H (sp2, sp3) functionalizations, which can be applied to the synthesis of biologically active natural products.
Also engaged in the development of new catalytic synthetic methods for the production of industrial-relevant fine chemicals and pharmaceuticals. Important goals are the efficient conversion of starting materials to the desired products, in particular with respect to chemo-, regio- and stereoselectivity.
Functionalization of C-H bond
Studies on Ruthenium Nitrosyls
We have been working on the designing and synthesis of ruthenium nitrosyl complexes for several biological applications such as anticancer, antibacterial, and wound healing studies.